Retatrutide
Triple agonist · GIP / GLP-1 / Glucagon
10mg · Lyophilized
Triple receptor agonist targeting GIP, GLP-1, and glucagon receptors simultaneously. The broadest-spectrum metabolic research compound currently available — addressing appetite, insulin regulation, fat storage, and energy expenditure in a single molecule.
About this compound
Mechanism and research context.
Retatrutide is a synthetic triple receptor agonist of the GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide 1), and glucagon receptors. It belongs to an emerging class of broad-spectrum metabolic research compounds being investigated in clinical settings.
Published clinical research has examined Retatrutide's effects on body weight, glycemic control, and visceral adiposity in obesity and Type 2 diabetes populations. The triple-agonist mechanism produces complementary effects: GLP-1 receptor activation modulates appetite and insulin secretion, GIP receptor activation contributes to insulin sensitivity and energy expenditure, and glucagon receptor activation increases basal metabolic rate and hepatic lipid oxidation.
Retatrutide is in late-stage clinical trials at the time of writing and represents the broadest receptor-agonism spectrum yet developed in this research class.
What ships
One vial. Independently verified.
Lyophilized.
Freeze-dried, sealed under inert gas. 2–3 year shelf life unopened at room temperature.
10mg · Lyophilized.
Quantity and format as listed. Discreet, tracked packaging anywhere in Canada.
Batch report available.
Canadian-lab verification report is available in the Resources section.
Dispatch within 48h.
Orders confirmed and dispatched from our Canadian facility within 48 hours.
How this batch was verified
Verified in Canada before listing.
Vetted manufacturing source.
Compounds sourced only from manufacturers who have been through extensive evaluation and vetting in our sourcing and procurement program.
Canadian lab verification — before shipping.
Every batch is independently tested at a Canadian laboratory before it lists. Verified in-country with full chain of custody — not sent overseas. The report we publish is from an independent Canadian lab, not the manufacturer or a third party lab outside of Canada.
Reconstitution guidance
Four steps. Standard across compounds.
Draw bacteriostatic water.
Use a reconstitution syringe to draw BAC water (bacteriostatic water, 0.9% benzyl alcohol).
Add slowly to the lyophilized vial.
Inject the water against the inside of the vial wall — do not shake.
Swirl until fully dissolved.
Gentle agitation only. The lyophilized cake should fully dissolve within a minute.
Refrigerate.
Reconstituted solution is typically stable for 28 days refrigerated.
Research use only
This product is sold strictly for research purposes and is not intended for human use, diagnosis, treatment, or prevention of any medical condition. It is not a licensed drug product under Health Canada regulations.
PRL does not provide dosing, protocol, or therapeutic guidance. Purchasers are responsible for ensuring their use complies with all applicable laws.